STOK Logo

Stoke Therapeutics, Inc. (STOK) 

NASDAQ
Market Cap
$673.4M
Sector
Healthcare
Industry
Biotechnology
Rank in Sector
759 of 809
Rank in Industry
416 of 445

Largest Insider Buys in Sector

STOK Stock Price History Chart

STOK Stock Performance

About Stoke Therapeutics, Inc.

Stoke Therapeutics, Inc., an early-stage biopharmaceutical company, develops novel antisense oligonucleotide (ASO) medicines to treat the underlying causes of severe genetic diseases in the United States. The company utilizes its proprietary Targeted Augmentation of Nuclear Gene Output to design ASOs to precisely upregulate protein expression. Its lead clinical candidate is STK-001, which is in phase I/IIa clinical trial to treat Dravet syndrome, a severe and progressive genetic epilepsy; and STK-002, which is in preclinical stage for the treatment of autosomal dominant optic atrophy. It had entered into a license and collaboration agreement with Acadia Pharmaceuticals Inc. for the discovery, development, and commercialization of novel RNA-based medicines for the treatment of severe and rare genetic neurodevelopmental diseases of the central nervous system. The company was formerly known as ASOthera Pharmaceuticals, Inc. and changed its name to Stoke Therapeutics, Inc. in May 2016. Stoke Therapeutics, Inc. was incorporated in 2014 and is headquartered in Bedford, Massachusetts.

Insider Activity of Stoke Therapeutics, Inc.

Over the last 12 months, insiders at Stoke Therapeutics, Inc. have bought $0 and sold $45.08M worth of Stoke Therapeutics, Inc. stock.

On average, over the past 5 years, insiders at Stoke Therapeutics, Inc. have bought $17.49M and sold $13.52M worth of stock each year.

There was no buying activity among insiders over the last 12 months.

The last purchase of 375,000 shares for transaction amount of $14.63M was made by Harrison Seth Loring () on 2020‑11‑24.

List of Insider Buy and Sell Transactions, Stoke Therapeutics, Inc.

2024-06-03SaleTicho BarryCHIEF MEDICAL OFFICER
10,000
0.0189%
$15.22$152,185-1.81%
2024-05-20SaleKaye Edward M. MDCEO
42,350
0.0779%
$15.43$653,529-7.01%
2024-05-20SaleAllan JonathanGENERAL COUNSEL & CORP SEC
8,599
0.0154%
$15.04$129,327-7.01%
2024-05-20SaleNash Huw M.COO & CBO
50,000
0.0917%
$15.39$769,500-7.01%
2024-05-01SaleTicho BarryCHIEF MEDICAL OFFICER
10,000
0.0189%
$11.37$113,653+24.55%
2024-04-17SaleSkorpios Trust10 percent owner
3.6M
6.8708%
$11.60$41.76M+19.49%
2024-04-01SaleTicho BarryCHIEF MEDICAL OFFICER
9,426
0.02%
$13.23$124,684-2.89%
2024-04-01SaleNash Huw M.COO & CBO
61,329
0.1299%
$13.23$811,212-2.89%
2024-03-28SaleAllan JonathanGENERAL COUNSEL & CORP SEC
5,126
0.0108%
$13.20$67,668-1.52%
2024-03-19SaleKaye Edward M. MDCEO
11,150
0.0263%
$6.10$67,999+125.30%
2024-03-19SaleTulipano Stephen JCFO
4,116
0.0097%
$6.10$25,102+125.30%
2024-03-19SaleTicho BarryCHIEF MEDICAL OFFICER
4,116
0.0097%
$6.10$25,102+125.30%
2024-03-19SaleNash Huw M.COO & CBO
4,116
0.0097%
$6.10$25,102+125.30%
2024-03-19SaleAllan JonathanGENERAL COUNSEL & CORP SEC
2,349
0.0055%
$6.10$14,326+125.30%
2024-03-01SaleTicho BarryCHIEF MEDICAL OFFICER
10,000
0.0231%
$7.75$77,469+64.10%
2024-02-01SaleTicho BarryCHIEF MEDICAL OFFICER
10,000
0.022%
$4.80$47,991+142.54%
2024-01-02SaleTicho BarryChief Medical Officer
10,000
0.0218%
$5.74$57,352+91.57%
2023-07-03SaleTicho BarryChief Medical Officer
15,000
0.0351%
$10.60$158,973-47.94%
2023-06-21SaleAllan JonathanGeneral Counsel & Corp Sec
1,948
0.0046%
$13.48$26,252-58.67%
2023-06-01SaleTicho BarryChief Medical Officer
15,000
0.0348%
$11.13$166,964-50.62%

Insider Historical Profitability

<0.0001%
Skorpios Trust10 percent owner
10843681
20.9098%
$12.9201
Ticho BarryCHIEF MEDICAL OFFICER
2485
0.0156%
$12.92021
Tulipano Stephen JCFO
20746
0.0013%
$12.9206
Nash Huw M.COO & CBO
0
0%
$12.92029
Allan JonathanGeneral Counsel & Corp Sec
2598
0%
$12.9204
Kaye Edward M. MDCEO
27000
0%
$12.9206
Harrison Seth Loring
17161713
38.4328%
$12.9220<0.0001%
Apple Tree Partners IV, L.P.10 percent owner
17161713
38.4328%
$12.9220<0.0001%
RTW INVESTMENTS, LP10 percent owner
3544248
7.9372%
$12.9261<0.0001%
Liau GeneEVP Research & Preclinical Dev
21351
0.0478%
$12.9207
LEVIN ARTHUR Adirector
0
0%
$12.9201
Walker Robin A.Chief Legal Officer, CCO & Sec
0
0%
$12.9201
TZIANABOS ARTHURdirector
0
0%
$12.9202

Institutional Investor Ownership

Top Shareholders
Top Buyers
Top Sellers
New Shareholders
Sold-Out Shareholders
Skorpios Trust$194.99M27.7114.44M0%+$099.92
Redmile Group$68.49M9.735.07M+93.22%+$33.04M2.54
RTW Investments, LP$57.04M8.114.22M+2.27%+$1.27M0.84
Morgan Stanley$54.34M7.724.03M+19.42%+$8.84M<0.01
BlackRock$52.09M7.43.86M+87.28%+$24.28M<0.01
Lynx1 Capital Management Lp$49.91M7.093.7M+25.02%+$9.99M2.63
Baker Bros Advisors LP$45.47M6.463.37M+65.92%+$18.07M0.57
Cowen Group$45.44M6.463.37M-9.56%-$4.8M1.44
The Vanguard Group$23.16M3.291.72M+4.07%+$905,202.00<0.0001
Goldman Sachs$18.95M2.691.4M+0.91%+$170,424.00<0.01
Franklin Templeton Investments$14.29M2.031.06MNew+$14.29M<0.01
Geode Capital Management$8.64M1.23639,807+3.91%+$325,156.50<0.01
State Street$7.82M1.11579,607+6.64%+$486,999.03<0.0001
Granahan Investment Management$6.42M0.91475,463-58.22%-$8.94M0.23
Cormorant Asset Management Lp$5.77M0.82427,163-60.73%-$8.92M0.27
Deutsche Bank$5.57M0.79412,240-0.13%-$7,263.00<0.01
Fidelity Investments$5.07M0.72375,481+7,409.62%+$5M<0.0001
Artal Group S A$4.05M0.58300,000New+$4.05M0.02
Eversept Partners LP$3.92M0.56290,000New+$3.92M0.3
Healthcare Of Ontario Pension Plan Trust Fund$3.56M0.51263,700+10.2%+$329,400.000.01
Northern Trust$3.52M0.5260,891+1.28%+$44,536.51<0.01
Sio Capital Management LLC$3.04M0.43225,496New+$3.04M1.08
Charles Schwab$3.01M0.43223,038+8.67%+$240,246.00<0.01
Dimensional Fund Advisors$2.97M0.42219,765+2.08%+$60,358.53<0.01
Birchview Capital Lp$2.83M0.4210,0000%+$00.16
D. E. Shaw & Co.$2.62M0.37193,760+35.77%+$689,161.76<0.01
Marshall Wace$2.41M0.34178,586New+$2.41M<0.01
DAFNA Capital Management, LLC$1.96M0.28145,000New+$1.96M0.46
Wellington Management Company$1.94M0.28143,351New+$1.94M<0.0001
Point72 Asset Management$1.92M0.27142,458New+$1.92M<0.01
Palo Alto Investors Lp$1.7M0.24125,861New+$1.7M0.19
Nuveen$1.62M0.23119,811+89.18%+$762,480.24<0.0001
Woodline Partners LP$1.44M0.21106,904+87.87%+$675,000.000.01
Maven Securities Ltd$1.35M0.19100,000New+$1.35M0.08
Laurion Capital Management LP$1.35M0.19100,000New+$1.35M0.04
Gsa Capital Partners Llp$1.32M0.1997,508-4.5%-$62,069.610.11
Mirae Asset Global Investments Co Ltd$728,024.000.1790,663New+$728,024.00<0.01
BNY Mellon$1.21M0.1789,904-8.57%-$113,724.09<0.0001
Gilder Gagnon Howe & Co. LLC$1.21M0.1789,783+44.23%+$371,722.650.02
Susquehanna International Group$1.07M0.1579,526+273.64%+$786,267.73<0.01
Fort Point Capital Partners$1.02M0.1575,4290%+$00.14
Monashee Investment Management LLC$912,384.000.1367,584New+$912,384.000.08
Los Angeles Capital Management LLC$840,470.000.1262,2570%+$0<0.01
Squarepoint Ops LLC$689,810.000.151,097+167.58%+$432,013.81<0.01
LMR PARTNERS LLP$675,000.000.150,000New+$675,000.000.02
Jacobs Levy Equity Management$646,812.000.0947,912-71.49%-$1.62M<0.01
State of Wisconsin Investment Board$650,700.000.0948,200-44.34%-$518,400.00<0.01
Eam Investors$618,908.000.0945,845New+$618,908.000.1
Millennium Management LLC$620,784.000.0945,984+92.29%+$297,945.00<0.0001
RhumbLine Advisers$565,239.000.0841,870+2.19%+$12,136.37<0.01