PepGen Inc., a clinical-stage biotechnology company, focuses on the development of oligonucleotide therapeutics for use in the treatment of severe neuromuscular and neurologic diseases. The company's lead product candidate is PGN-EDO51, an EDO peptide in Phase I clinical trials to treat individuals with Duchenne muscular dystrophy (DMD). It is also developing PGN-EDODM1, an EDO peptide-conjugated PMO for the treatment of myotonic dystrophy type 1, as well as EDO therapeutic candidates, such as PGN-EDO53, PGN-EDO45, and PGN-EDO44 for the treatment of DMD. The company was founded in 2018 and is headquartered in Cambridge, Massachusetts.
Over the last 12 months, insiders at PepGen Inc. have bought $27.21M and sold $1.04M worth of PepGen Inc. stock.
On average, over the past 5 years, insiders at PepGen Inc. have bought $14.44M and sold $827,860 worth of stock each year.
Highest buying activity among insiders over the last 12 months: RA CAPITAL MANAGEMENT, L.P. () — $816.38M.
The last purchase of 2,557,593 shares for transaction amount of $27.21M was made by RA CAPITAL MANAGEMENT, L.P. () on 2024‑02‑09.
2024-07-25 | Sale | Chief Medical Officer | 7,571 0.0234% | $18.06 | $136,741 | -52.00% | ||
2024-07-24 | Sale | Chief Medical Officer | 201 0.0006% | $18.01 | $3,619 | 0.00% | ||
2024-07-18 | Sale | Chief Medical Officer | 12,625 0.0427% | $18.20 | $229,804 | -47.59% | ||
2024-07-16 | Sale | Chief Medical Officer | 5,901 0.0194% | $18.00 | $106,247 | -51.50% | ||
2024-07-12 | Sale | Chief Medical Officer | 3,288 0.0108% | $18.04 | $59,331 | 0.00% | ||
2024-07-02 | Sale | Chief Medical Officer | 37 0.0001% | $18.07 | $669 | 0.00% | ||
2024-07-01 | Sale | Chief Medical Officer | 875 0.0029% | $18.01 | $15,760 | 0.00% | ||
2024-06-24 | Sale | Chief Medical Officer | 9,260 0.0291% | $18.19 | $168,427 | -50.62% | ||
2024-06-12 | Sale | Chief Medical Officer | 1,086 0.0034% | $18.06 | $19,615 | -49.94% | ||
2024-06-11 | Sale | Chief Medical Officer | 500 0.0016% | $18.04 | $9,022 | -50.50% | ||
2024-06-06 | Sale | SVP, Clinical Development | 1,411 0.0045% | $18.00 | $25,398 | -48.79% | ||
2024-06-05 | Sale | SVP, Clinical Development | 7,245 0.0223% | $18.09 | $131,062 | -51.05% | ||
2024-05-17 | Sale | SVP, Chem. Mfg & Controls | 10,000 0.0306% | $13.41 | $134,100 | -31.95% | ||
2024-02-09 | 2.56M 10.4935% | $10.64 | $27.21M | -20.94% | ||||
2023-11-30 | President and CEO | 1,694 0.006% | $4.17 | $7,056 | +115.41% | |||
2023-06-08 | Sale | President and CEO | 2,381 0.0098% | $16.04 | $38,188 | -54.91% | ||
2023-06-07 | Sale | President and CEO | 8,419 0.0366% | $16.23 | $136,618 | -52.77% | ||
2023-06-06 | Sale | President and CEO | 18,150 0.076% | $16.18 | $293,660 | -54.30% | ||
2023-06-05 | Sale | President and CEO | 500 0.0022% | $16.06 | $8,028 | -52.58% | ||
2023-06-02 | Sale | President and CEO | 1,800 0.0075% | $16.04 | $28,863 | -54.46% |
RA CAPITAL MANAGEMENT, L.P. | 9179273 28.161% | $2.41 | 1 | 0 | ||
Svenstrup Niels | SVP, Chem. Mfg & Controls | 0 0% | $2.41 | 0 | 1 | |
Mellion Michelle L | Chief Medical Officer | 0 0% | $2.41 | 0 | 12 | |
Oxford Science Enterprises plc | 10 percent owner | 4755388 14.589% | $2.41 | 1 | 0 | |
Shah Rajeev M. | 1302600 3.9962% | $2.41 | 1 | 0 | +7.35% | |
Deerfield Private Design Fund V, L.P. | 476813 1.4628% | $2.41 | 1 | 0 | +7.35% | |
KEATING LAURIE | director | 4166 0.0128% | $2.41 | 1 | 0 | <0.0001% |
McArthur James G | President and CEO | 1694 0.0052% | $2.41 | 1 | 5 | |
Goyal Jaya | EVP, Res. & Preclin. Dev. | 0 0% | $2.41 | 0 | 4 |
RA Capital Management, L.P. | $157.14M | 32.98 | 10.69M | +31.45% | +$37.6M | 0.16 | |
Suvretta Capital Management, LLC | $22.36M | 4.69 | 1.52M | +212.56% | +$15.2M | 0.94 | |
Frazier Life Sciences Management L P | $22.09M | 4.64 | 1.5M | New | +$22.09M | 1 | |
Viking Global Investors | $21.79M | 4.57 | 1.48M | 0% | +$0 | 0.01 | |
Perceptive Advisors | $20.73M | 4.35 | 1.41M | New | +$20.73M | 0.01 | |
Adage Capital Partners Gp L L C | $19.6M | 4.11 | 1.33M | +21.24% | +$3.43M | 0.04 | |
Janus Henderson | $17.23M | 3.6 | 1.17M | +18.06% | +$2.63M | 0.01 | |
The Vanguard Group | $12.5M | 2.62 | 850,445 | +68.01% | +$5.06M | <0.0001 | |
Laurion Capital Management LP | $12.37M | 2.6 | 841,431 | +26.62% | +$2.6M | 0.09 | |
BlackRock | $11.49M | 2.41 | 781,437 | +8% | +$851,115.31 | <0.0001 | |
Sofinnova | $7.4M | 1.55 | 503,624 | +2,086.06% | +$7.06M | 0.02 | |
Fidelity Investments | $6.74M | 1.42 | 458,640 | -37.86% | -$4.11M | <0.0001 | |
Octagon Capital Advisors LP | $5.53M | 1.16 | 376,117 | New | +$5.53M | 0.03 | |
Geode Capital Management | $4.4M | 0.92 | 299,487 | +42.58% | +$1.31M | <0.0001 | |
State Street | $3.54M | 0.74 | 240,982 | +11.1% | +$353,799.56 | <0.0001 | |
Artal Group S A | $2.94M | 0.62 | 200,000 | New | +$2.94M | 0.01 | |
Point72 Asset Management | $2.83M | 0.59 | 192,178 | New | +$2.83M | <0.01 | |
Bridgeway Capital Management | $1.46M | 0.31 | 99,200 | 0% | +$0 | 0.02 | |
Northern Trust | $1.36M | 0.28 | 92,195 | +23.21% | +$255,338.91 | <0.0001 | |
Monashee Investment Management LLC | $1.26M | 0.27 | 85,886 | New | +$1.26M | 0.11 | |
Walleye Capital | $949,826.00 | 0.2 | 64,614 | New | +$949,826.00 | <0.01 | |
Citigroup | $596,967.00 | 0.13 | 40,610 | +2,864.23% | +$576,828.00 | <0.0001 | |
Crestline Management Lp | $514,500.00 | 0.11 | 35,000 | New | +$514,500.00 | 0.05 | |
Rathbone Brothers | $470,444.00 | 0.1 | 32,003 | -48.38% | -$440,999.91 | <0.01 | |
Charles Schwab | $459,963.00 | 0.1 | 31,290 | +12.59% | +$51,450.00 | <0.0001 | |
BNY Mellon | $452,172.00 | 0.1 | 30,760 | -2.09% | -$9,672.60 | <0.0001 | |
Morgan Stanley | $418,685.00 | 0.09 | 28,482 | -20.7% | -$109,294.40 | <0.0001 | |
Qube Research & Technologies | $364,354.00 | 0.08 | 24,786 | +20,051.22% | +$362,545.90 | <0.0001 | |
Bank of America | $280,138.00 | 0.06 | 19,057 | +20.69% | +$48,024.92 | <0.0001 | |
American Century Investments | $245,519.00 | 0.05 | 16,702 | New | +$245,519.00 | <0.0001 | |
JPMorgan Chase | $227,586.00 | 0.05 | 15,482 | +52.64% | +$78,483.51 | <0.0001 | |
Nuveen | $203,566.00 | 0.04 | 13,848 | 0% | +$0 | <0.0001 | |
RhumbLine Advisers | $203,602.00 | 0.04 | 13,851 | +0.07% | +$146.99 | <0.0001 | |
Goldman Sachs | $194,231.00 | 0.04 | 13,213 | -6.66% | -$13,862.09 | <0.0001 | |
AllianceBernstein | $177,282.00 | 0.04 | 12,060 | 0% | +$0 | <0.0001 | |
UBS | $147,838.00 | 0.03 | 10,057 | -7.85% | -$12,597.91 | <0.0001 | |
Barclays | $103,000.00 | 0.02 | 7,003 | -48.97% | -$98,852.35 | <0.0001 | |
New York State Common Retirement Fund | $95,000.00 | 0.02 | 6,480 | -0.05% | -$43.98 | <0.0001 | |
MetLife Investment Management | $85,172.00 | 0.02 | 5,794 | New | +$85,172.00 | <0.01 | |
American International Group | $72,809.00 | 0.02 | 4,953 | -0.86% | -$632.10 | <0.0001 | |
Deutsche Bank | $62,166.00 | 0.01 | 4,229 | New | +$62,166.00 | <0.0001 | |
Wells Fargo | $51,097.00 | 0.01 | 3,476 | +16.88% | +$7,379.37 | <0.0001 | |
Ohio Strs | $52,000.00 | 0.01 | 3,600 | +89.47% | +$24,555.56 | <0.0001 | |
Acadian Asset Management | $30,000.00 | 0.01 | 2,052 | New | +$30,000.00 | <0.0001 | |
Ameritas Investment Partners Inc | $17,273.00 | <0.01 | 1,175 | 0% | +$0 | <0.01 | |
CalSTRS | $14,847.00 | <0.01 | 1,010 | -38.94% | -$9,466.80 | <0.0001 | |
Legal & General | $12,539.00 | <0.01 | 853 | 0% | +$0 | <0.0001 | |
MetLife | $8,761.00 | <0.01 | 596 | New | +$8,761.00 | <0.0001 | |
Amalgamated Bank | $5,000.00 | <0.01 | 337 | -72.22% | -$12,997.03 | <0.0001 | |
Tower Research Capital | $3,954.00 | <0.01 | 269 | -84.72% | -$21,916.04 | <0.0001 |